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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr80em1Jwsk
endonuclease-mediated mutation 1, Joanna Wysocka
MGI:6720282
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr80em1Jwsk/Rr80em1Jwsk involves: C57BL/6J * FVB/NJ MGI:6720289
cn2
 		Sox9tm2Crm/Sox9+
Rr80em1Jwsk/Rr80+
E2f1Tg(Wnt1-cre)2Sor/E2f1+ 		involves: 129S7/SvEvBrd * C3H * C57BL/6J * FVB/NJ MGI:6720292


Genotype
MGI:6720289
hm1
Allelic
Composition		 Rr80em1Jwsk/Rr80em1Jwsk
Genetic
Background		 involves: C57BL/6J * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial

skeleton




Genotype
MGI:6720292
cn2
Allelic
Composition		 Sox9tm2Crm/Sox9+
Rr80em1Jwsk/Rr80+
E2f1Tg(Wnt1-cre)2Sor/E2f1+
Genetic
Background		 involves: 129S7/SvEvBrd * C3H * C57BL/6J * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (25 available)
Rr80em1Jwsk mutation (0 available); any Rr80 mutation (0 available)
Sox9tm2Crm mutation (1 available); any Sox9 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal mandible morphology ( J:306395 )
• exacerbated compared with wild-type enhancer cluster 1.45

growth/size/body
postnatal growth retardation ( J:306395 )

skeleton
abnormal mandible morphology ( J:306395 )
• exacerbated compared with wild-type enhancer cluster 1.45




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory