Phenotypes associated with this allele

• Allele Symbol: Zfp800^em1Mgn
• Allele Name: endonuclease-mediated mutation 1, Mark A Magnuson
• Allele ID: MGI:6716236
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp800^em1Mgn/Zfp800^em1Mgn	B6.Cg-Zfp800^em1Mgn/Vu	MGI:6716257

Genotype
MGI:6716257

hm1

• Allelic Composition: Zfp800^em1Mgn/Zfp800^em1Mgn
• Genetic Background: B6.Cg-Zfp800^em1Mgn/Vu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:306470 )

• mice die a few days after birth

endocrine/exocrine glands

abnormal pancreatic acinar cell morphology ( J:306470 )

• defective polarity and organization

decreased PP cell number ( J:306470 )

• at E18.5

decreased pancreatic alpha cell number ( J:306470 )

• at E18.5

decreased pancreatic beta cell number ( J:306470 )

• at E18.5

decreased pancreatic delta cell number ( J:306470 )

• at E18.5

abnormal endocrine pancreas development ( J:306470 )

• impaired in E18.5 embryos with reduced insulin, glucagon, somatostatin and pancreatic polypeptide-positive cell

digestive/alimentary system

abnormal pancreatic acinar cell morphology ( J:306470 )

• defective polarity and organization