About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		St8sia3em3Yich
endonuclease-mediated mutation 3, Yijuang Chern
MGI:6711696
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		St8sia3em3Yich/St8sia3em3Yich C57BL/6JNarl-St8sia3em3Yich MGI:6711809


Genotype
MGI:6711809
hm1
Allelic
Composition		 St8sia3em3Yich/St8sia3em3Yich
Genetic
Background		 C57BL/6JNarl-St8sia3em3Yich
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St8sia3em3Yich mutation (0 available); any St8sia3 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal locomotor behavior ( J:285485 )
• normal spontaneous locomotor behavior
• less sensitive to increased motor activity effect of Adora2a (adenosine A2a receptor) antagonist SCH 58261
• more sensitive to reduced motor activity effect of (Drd2 (dopamine receptor D2) antagonist L-741626

homeostasis/metabolism
abnormal peptide metabolism ( J:285485 )
• reduced sialylation of N- and O-glycans in striatum




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory