Phenotypes associated with this allele

• Allele Symbol: Cbr1^tm1.1Tmnb
• Allele Name: targeted mutation 1.1, Toshiya Manabe
• Allele ID: MGI:6704988
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Cbr1^tm1.1Tmnb/Cbr1^+ Ts(16C-tel)1Cje/0	involves: C57BL/6J * FVB/N	MGI:6712753

Genotype
MGI:6712753

cx1

• Allelic Composition: Cbr1^tm1.1Tmnb/Cbr1⁺; Ts(16C-tel)1Cje/0
• Genetic Background: involves: C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:294908 )

N • the deficit in spatial memory accuracy in the Barnes maze task seen in Ts(16C-tel)1Cje/0 mice is partially improved

increased locomotor activity ( J:294908 )

• mice travel longer distances than wild-type mice

decreased stereotypic behavior ( J:294908 )

• the number of stereotypic events (repetitive movements detected by laser sensors) is decreased

growth/size/body

decreased body weight ( J:294908 )

• 21-week old mice exhibit decreased body weight

nervous system

abnormal nervous system electrophysiology ( J:294908 )

• later phase of the depolarization envelope during long-term potentiation (LTP)-inducing stimulation is smaller