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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ganabem#Xche
endonuclease-mediated mutation, Xiangmei Chen
MGI:6695176
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ganabem#Xche/Ganabem#Xche involves: C57BL/6 MGI:6695180
ht2
 		Ganabem#Xche/Ganab+ involves: C57BL/6 MGI:6695181


Genotype
MGI:6695180
hm1
Allelic
Composition		 Ganabem#Xche/Ganabem#Xche
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ganabem#Xche mutation (0 available); any Ganab mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:304107 )
• early embryonic lethality, with no live embryos seen past E3.5




Genotype
MGI:6695181
ht2
Allelic
Composition		 Ganabem#Xche/Ganab+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ganabem#Xche mutation (0 available); any Ganab mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:304107 )
• mice show no cysts in the kidneys or livers and do not show any abnormal clinical phenotypes after birth, with no renal tubule dilatation or glomeruli abnormalities




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory