All Phenotypes Ces5a<em1Zuk> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ces5a^em1Zuk
endonuclease-mediated mutation 1, Martin M Matzuk
MGI:6693654

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ces5a^em1Zuk/Ces5a^em1Zuk	involves: C57BL/6 * DBA/2	MGI:6693754

Allelic Composition	Ces5a^em1Zuk/Ces5a^em1Zuk
Genetic Background	involves: C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ces5a^em1Zuk mutation (0 available); any Ces5a mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:295177 )

N	• mice exhibit normal testis histology and sperm morphology

oligozoospermia ( J:295177 )

• with decreased average path velocity and progressive velocity after hyperactivation

asthenozoospermia ( J:295177 )

abnormal epididymis morphology ( J:295177 )

• dilated lumen, inflammation, and abnormal epithelia

reduced male fertility ( J:295177 )

• male mice sire fewer litters and pups

• however, litter size is normal over 3 month mating period

cellular

oligozoospermia ( J:295177 )

• with decreased average path velocity and progressive velocity after hyperactivation

asthenozoospermia ( J:295177 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23