All Phenotypes Nemp1<em1Hmc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nemp1^em1Hmc
endonuclease-mediated mutation 1, Helen McNeill
MGI:6693344

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nemp1^em1Hmc/Nemp1^em1Hmc	C57BL/6N-Nemp1^em1Hmc	MGI:6693346

Allelic Composition	Nemp1^em1Hmc/Nemp1^em1Hmc
Genetic Background	C57BL/6N-Nemp1^em1Hmc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nemp1^em1Hmc mutation (0 available); any Nemp1 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:303621 )

N	• male mice are fertile

abnormal oocyte morphology ( J:303621 )

• reduced nuclear envelop stiffness

abnormal female meiosis ( J:303621 )

• increasing with maternal age

female infertility ( J:303621 )

• female mice are infertile or subfertile

reduced female fertility ( J:303621 )

• female mice are infertile or subfertile

hematopoietic system

anemia ( J:303621 )

endocrine/exocrine glands

cellular

abnormal oocyte morphology ( J:303621 )

• reduced nuclear envelop stiffness

abnormal female meiosis ( J:303621 )

• increasing with maternal age

maternal effect ( J:303621 )

• zygotes from null oocytes fertilized with wild-type sperm fail to develop beyond the 8 cell stage

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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