behavior/neurological
N |
• normal behavior in rotarod, traction and pole tests
(J:302698)
• normal cognitive behavior
(J:302698)
|
N |
• normal speed in light-dark test
(J:302698)
|
• fewer center square entries and less time spent there in open field test (OFT)
(J:302698)
• fewer open arm entries in elevated zero-maze (EZM) test
(J:302698)
|
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• fewer light compartment entries and less time spent there in light-dark test
(J:302698)
• longer latency to feed in novelty-suppressed feeding (NSF) test
(J:302698)
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• fewer center square entries and less time spent there in open field test (OFT)
• fewer open arm entries in elevated zero-maze (EZM) test
|
nervous system
N |
• normal Na+ and K+ currents in basolateral amygdaloid nucleus (BLA) and medial prefrontal cortex (mPFC) neurons
• normal medium after-hyperpolarization (mAHP) potential in basolateral amygdaloid nucleus (BLA) and medial prefrontal cortex (mPFC) neurons
|
• lower current density of hyperpolarization-activated cyclic nucleotidegated (HCN) channels in BLA pyramidal neurons
(J:302698)
• slower activation kinetics in BLA pyramidal neurons
(J:302698)
• normal membrane capacitance in basolateral amygdaloid nucleus (BLA) pyramidal neurons
(J:302698)
|
|
• higher input resistance and membrane time constant in basolateral amygdaloid nucleus (BLA) pyramidal neurons
(J:302698)
• BLA pyramidal neurons are more sensitive to depolarizing current injections and are more excitable
(J:302698)
• smaller voltage drop in response to hyperpolarizing current injection in BLA pyramidal neurons
(J:302698)
• lower hyperpolarizing current amplitude in BLA pyramidal neurons
(J:302698)
|
growth/size/body
N |
• normal body and organ weights
|