Phenotypes associated with this allele

• Allele Symbol: Fitm1^tm1Nani
• Allele Name: targeted mutation 1, Natsumi Nishihama
• Allele ID: MGI:6690472
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fitm1^tm1Nani/Fitm1^tm1Nani	Not Specified	MGI:6690501

Genotype
MGI:6690501

hm1

• Allelic Composition: Fitm1^tm1Nani/Fitm1^tm1Nani
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:303195 )

N • normal left ventricular end-diastolic dimension (LVDd), left ventricular end-systolic dimension (LVDs) and ejection fraction at age 22 months

N • normal left and right ventricular weight at age 24 months

N • normal left ventricle expansion and ejection fraction reduction up to 8 weeks after trans-aortic constriction (TAC)

N • normal heart right ventricle weight increase after trans-aortic constriction (TAC)

increased heart left ventricle weight ( J:303195 )

• increased weight after trans-aortic constriction (TAC)

growth/size/body

growth/size/body region phenotype ( J:303195 )

N • normal body weight at age 22 and 24 months

N • normal body weight reduction 8 weeks after trans-aortic constriction (TAC)

mortality/aging

mortality/aging ( J:303195 )

N • viable

decreased susceptibility to induced morbidity/mortality ( J:303195 )

• increased survival after trans-aortic constriction (TAC)

respiratory system

respiratory system phenotype ( J:303195 )

N • normal lung weight increase after trans-aortic constriction (TAC)