About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pabpn1lem1Hyfn
endonuclease-mediated mutation 1, Heng-Yu Fan
MGI:6509577
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pabpn1lem1Hyfn/Pabpn1lem1Hyfn C57BL/6-Pabpn1lem1Hyfn MGI:6693343


Genotype
MGI:6693343
hm1
Allelic
Composition		 Pabpn1lem1Hyfn/Pabpn1lem1Hyfn
Genetic
Background		 C57BL/6-Pabpn1lem1Hyfn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pabpn1lem1Hyfn mutation (0 available); any Pabpn1l mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:302699 )
N
• male mice exhibit normal fertility
abnormal oocyte morphology ( J:302699 )
• increased maternal RNA in oocytes
female infertility ( J:302699 )
• despite normal MII oocyte numbers

cellular
abnormal oocyte morphology ( J:302699 )
• increased maternal RNA in oocytes
maternal effect ( J:302699 )
• regardless of embryo genotype, zygotes arrest at 1- to 2-cell stage and fail to develop further




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory