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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ddx39bem1Cya
endonuclease-mediated mutation 1, Cyagen Biosciences
MGI:6509428
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ddx39bem1Cya/Ddx39bem1Cya C57BL/6N-Ddx39bem1Cya/Cya MGI:6509430
ht2
 		Ddx39bem1Cya/Ddx39b+ C57BL/6N-Ddx39bem1Cya/Cya MGI:6509437


Genotype
MGI:6509430
hm1
Allelic
Composition		 Ddx39bem1Cya/Ddx39bem1Cya
Genetic
Background		 C57BL/6N-Ddx39bem1Cya/Cya
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddx39bem1Cya mutation (0 available); any Ddx39b mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:299665 )
• no mice are present at 3 weeks of age




Genotype
MGI:6509437
ht2
Allelic
Composition		 Ddx39bem1Cya/Ddx39b+
Genetic
Background		 C57BL/6N-Ddx39bem1Cya/Cya
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddx39bem1Cya mutation (0 available); any Ddx39b mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased cellular sensitivity to gamma-irradiation ( J:299665 )
• following gamma irradiation, mouse embryonic fibroblasts exhibit increased gammaH2AX foci compared with wild-type cells

homeostasis/metabolism

mortality/aging




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory