Phenotypes associated with this allele

• Allele Symbol: Gabrg1^em1Ktka
• Allele Name: endonuclease-mediated mutation 1, Kristopher T Kahle
• Allele ID: MGI:6506870
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gabrg1^em1Ktka/Gabrg1^em1Ktka	involves: C57BL/6N	MGI:6506871

Genotype
MGI:6506871

hm1

• Allelic Composition: Gabrg1^em1Ktka/Gabrg1^em1Ktka
• Genetic Background: involves: C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal nocifensive behavior ( J:299761 )

• mice show significant nocifensive behaviors in response to tactile stimulation of the trigeminal nerve region in a version of a facial stimulation test

decreased mechanical nociceptive threshold ( J:299761 )

• mice show a lower nociceptive withdrawal threshold than wild-type mice in a modified mechanical threshold test

• hind paw nociceptive withdrawal threshold is reduced

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
trigeminal neuralgia		DOID:12098	OMIM:190400	J:299761