All Phenotypes Prdm9<em3Kpgn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prdm9^em3Kpgn
endonuclease-mediated mutation 3, Kenneth Paigen
MGI:6506065

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdm9^em3Kpgn/Prdm9^em3Kpgn	involves: C57BL/6J	MGI:6506421
cx2	Prdm9^em3Kpgn/Prdm9^em3Kpgn Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi}	involves: C57BL/6J * C57BL/6N	MGI:6506422

Allelic Composition	Prdm9^em3Kpgn/Prdm9^em3Kpgn
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm9^em3Kpgn mutation (0 available); any Prdm9 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

cellular phenotype ( J:280261 )

N	• normal number of double-strand DNA breaks in spermatocytes

Allelic Composition	Prdm9^em3Kpgn/Prdm9^em3Kpgn Stag3^{tm1e.1(KOMP)Wtsi}/Stag3^{tm1e.1(KOMP)Wtsi}
Genetic Background	involves: C57BL/6J * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm9^em3Kpgn mutation (0 available); any Prdm9 mutation (45 available)
Stag3^{tm1e.1(KOMP)Wtsi} mutation (1 available); any Stag3 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal double-strand DNA break repair ( J:280261 )

• severely reduced number of double-strand DNA breaks in spermatocytes

homeostasis/metabolism

abnormal double-strand DNA break repair ( J:280261 )

• severely reduced number of double-strand DNA breaks in spermatocytes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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