Phenotypes associated with this allele

• Allele Symbol: Pole3^em2Tbo
• Allele Name: endonuclease-mediated mutation 2, Thomas Boehm
• Allele ID: MGI:6490634
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pole3^em2Tbo/Pole3^em2Tbo	FVB-Pole3^em2Tbo	MGI:6491463

Genotype
MGI:6491463

hm1

• Allelic Composition: Pole3^em2Tbo/Pole3^em2Tbo
• Genetic Background: FVB-Pole3^em2Tbo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased lymphocyte cell number ( J:298827 )

• slight reduction in number of CD4+, CD8+ and CD19+ cells in spleen

decreased thymocyte number ( J:298827 )

• slight reduction

decreased B cell number ( J:298827 )

• slight reduction in number of B220+ cells in bone marrow

decreased splenocyte number ( J:298827 )

• slight reduction in number of CD4+, CD8+ and CD19+ cells in spleen

endocrine/exocrine glands

decreased thymocyte number ( J:298827 )

• slight reduction

hematopoietic system

decreased lymphocyte cell number ( J:298827 )

• slight reduction in number of CD4+, CD8+ and CD19+ cells in spleen

decreased thymocyte number ( J:298827 )

• slight reduction

decreased B cell number ( J:298827 )

• slight reduction in number of B220+ cells in bone marrow

decreased splenocyte number ( J:298827 )

• slight reduction in number of CD4+, CD8+ and CD19+ cells in spleen

embryo

embryo phenotype ( J:298827 )

N • no gross developmental anomalies

mortality/aging

mortality/aging ( J:298827 )

N • viable; born at expected Mendelian ratios