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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chd7em1Jiao
endonuclease-mediated mutation 1, Kai Jiao
MGI:6490625
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chd7em1Jiao/Chd7em1Jiao involves: 129S6/SvEvTac * C57BL/6 * SJL MGI:6490653


Genotype
MGI:6490653
hm1
Allelic
Composition		 Chd7em1Jiao/Chd7em1Jiao
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7em1Jiao mutation (0 available); any Chd7 mutation (134 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:298597 )
• all embryos die between E10.5 and E12.5, with 1/3 surviving to E11.5

growth/size/body
embryonic growth retardation ( J:298597 )
• embryos show developmental delay beginning at E10.5

embryo
embryonic growth arrest ( J:298597 )
• growth is arrested at the ~35 somite stage at E11.5
embryonic growth retardation ( J:298597 )
• embryos show developmental delay beginning at E10.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory