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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		N4bp1em1Vmd
endonuclease-mediated mutation 1, Vishva Dixit
MGI:6490607
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		N4bp1em1Vmd/N4bp1em1Vmd C57BL/6N-N4bp1em1Vmd MGI:6491437


Genotype
MGI:6491437
hm1
Allelic
Composition		 N4bp1em1Vmd/N4bp1em1Vmd
Genetic
Background		 C57BL/6N-N4bp1em1Vmd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
N4bp1em1Vmd mutation (0 available); any N4bp1 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:297419 )
N
• mice exhibit no substantial organ pathology or immune dysregulation
decreased interleukin-6 secretion ( J:297419 )
• in bone marrow-derived macrophages treated with poly(I:C) or LPS




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory