Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1em2Mem mutation
(0 available);
any
Fan1 mutation
(98 available)
|
|
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cellular
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• karyomegaly in the kidney at 5 months
|
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• in response to mitomycin C in embryonic fibroblasts
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1em2Mem mutation
(0 available);
any
Fan1 mutation
(98 available)
Htttm3Mem mutation
(1 available);
any
Htt mutation
(179 available)
|
|
|
cellular
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• some expansion of the Htt CAG triplet repeats in striatum and liver at 8 months of age
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Allelic Composition |
Fan1em2Mem/Fan1+ Htttm3Mem/Htt+
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Genetic Background |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1em2Mem mutation
(0 available);
any
Fan1 mutation
(98 available)
Htttm3Mem mutation
(1 available);
any
Htt mutation
(179 available)
|
|
|
cellular
|
• expansion of the Htt CAG triplet repeats in striatum and liver at 8 months of age
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1em2Mem mutation
(0 available);
any
Fan1 mutation
(98 available)
Htttm5Mem mutation
(2 available);
any
Htt mutation
(179 available)
|
|
|
cellular
|
• expansion of the Htt CAG triplet repeats in striatum and liver at 5 months of age
|