All Phenotypes Mtmr10<em1Mem> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mtmr10^em1Mem
endonuclease-mediated mutation 1, Marcy E MacDonald
MGI:6489291

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mtmr10^em1Mem/Mtmr10^em1Mem	C57BL/6J-Mtmr10^em1Mem	MGI:6489864
cx2	Htt^tm5Mem/Htt⁺ Mtmr10^em1Mem/Mtmr10^em1Mem	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:6489865

Allelic Composition	Mtmr10^em1Mem/Mtmr10^em1Mem
Genetic Background	C57BL/6J-Mtmr10^em1Mem

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtmr10^em1Mem mutation (0 available); any Mtmr10 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:298297 )

N	• mice exhibit normal preweaning survival

Allelic Composition	Htt^tm5Mem/Htt⁺ Mtmr10^em1Mem/Mtmr10^em1Mem
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htt^tm5Mem mutation (2 available); any Htt mutation (179 available)
Mtmr10^em1Mem mutation (0 available); any Mtmr10 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell physiology ( J:298297 )

• expansion of the Htt CAG triplet repeats in striatum and liver at 5 months of age

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