Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ankmy2tm1b(EUCOMM)Hmgu mutation
(0 available);
any
Ankmy2 mutation
(31 available)
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embryo
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• ventralized neural tube in E9.5 embryos (ventral cell types ectopically specified at expense of lateral and dorsal types) throughout rostrocaudal extent of spinal cord and hindbrain
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• neural fold still completely open at 1012 somite stage (E8.5)
• open brain regions and extensive rostral malformations
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mortality/aging
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• embryos are arrested at 1012 somite stage (E8.5) and dont turn
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nervous system
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• ventralized neural tube in E9.5 embryos (ventral cell types ectopically specified at expense of lateral and dorsal types) throughout rostrocaudal extent of spinal cord and hindbrain
|
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• neural fold still completely open at 1012 somite stage (E8.5)
• open brain regions and extensive rostral malformations
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ankmy2tm1b(EUCOMM)Hmgu mutation
(0 available);
any
Ankmy2 mutation
(31 available)
Ift88tm1Bky mutation
(1 available);
any
Ift88 mutation
(48 available)
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cardiovascular system
cellular
embryo
N |
• normal neural tube closure at 14-16 somite stage
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homeostasis/metabolism
mortality/aging
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• embryos are arrested at stage E9.5
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ankmy2tm1b(EUCOMM)Hmgu mutation
(0 available);
any
Ankmy2 mutation
(31 available)
Gli2tm1Alj mutation
(0 available);
any
Gli2 mutation
(169 available)
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embryo
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• limited ventralization of thoracic and lumbar level neural tube; extensive ventralization of cranial level neural tube
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• open neural tube in hindbrain area at 26-28 somite stage (E9.5)
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mortality/aging
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• embryos are arrested at 26-28 somite stage (E9.5)
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nervous system
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• limited ventralization of thoracic and lumbar level neural tube; extensive ventralization of cranial level neural tube
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• open neural tube in hindbrain area at 26-28 somite stage (E9.5)
|
|
• open neural tube in hindbrain area at 26-28 somite stage (E9.5)
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ankmy2tm1b(EUCOMM)Hmgu mutation
(0 available);
any
Ankmy2 mutation
(31 available)
Smotm1Amc mutation
(1 available);
any
Smo mutation
(39 available)
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|
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embryo
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• ventralized neural tube in E9.5 embryos (ventral cell types ectopically specified at expense of lateral and dorsal types) throughout rostrocaudal extent of spinal cord and hindbrain
|
mortality/aging
|
• embryos are arrested at 1012 somite stage (E8.5)
|
nervous system
|
• ventralized neural tube in E9.5 embryos (ventral cell types ectopically specified at expense of lateral and dorsal types) throughout rostrocaudal extent of spinal cord and hindbrain
|