All Phenotypes Slc25a11<em1Syki> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc25a11^em1Syki
endonuclease-mediated mutation 1, Soo-Youl Kim
MGI:6469639

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc25a11^em1Syki/Slc25a11^em1Syki	Not Specified	MGI:6469641
cx2	Slc25a11^em1Syki/Slc25a11⁺ Kras^tm3Tyj/Kras⁺	involves: 129S * C57BL/6	MGI:6469642

Allelic Composition	Slc25a11^em1Syki/Slc25a11^em1Syki
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a11^em1Syki mutation (0 available); any Slc25a11 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality ( J:294965 )

Allelic Composition	Slc25a11^em1Syki/Slc25a11⁺ Kras^tm3Tyj/Kras⁺
Genetic Background	involves: 129S * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kras^tm3Tyj mutation (2 available); any Kras mutation (76 available)
Slc25a11^em1Syki mutation (0 available); any Slc25a11 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased lung tumor incidence ( J:294965 )

• 60% reduction of number of tumor nodes at age 12 weeks

• 54% reduction in tumor area at age 12 weeks

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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