Analysis Tools|
Allele Symbol Allele Name Allele ID |
Gt(ROSA)26Sortm1(CARD14*)Ribt targeted mutation 1, Rudi Beyaert MGI:6459917 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice delivered by Caesarian section do not survive beyond 24 hours after birth
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| N |
• mice exhibit normal epidermal skin barrier function
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in tamoxifen-treated mice
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• in the basal layer of ear skin of tamoxifen-treated mice
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• reminiscent of Munros abscesses in the stratum corneum in tamoxifen-treated mice
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• in tamoxifen-treated mice
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• in tamoxifen-treated mice
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• in tamoxifen-treated mice
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• in tamoxifen-treated mice
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• from 6 weeks on, mice exhibit mild ear thickening unlike control mice
• tamoxifen-treated mice exhibit increased progressive ear swelling with ears becoming scaly and red unlike control mice
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• in the ear of tamoxifen-treated mice
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• in the ear of tamoxifen-treated mice
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• reminiscent of Munros abscesses in the stratum corneum in tamoxifen-treated mice
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• in tamoxifen-treated mice
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• in tamoxifen-treated mice
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• in the basal layer of ear skin of tamoxifen-treated mice
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• in the ear of tamoxifen-treated mice
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• in the ear of tamoxifen-treated mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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• from 6 weeks on, mice exhibit mild ear thickening unlike control mice
• tamoxifen-treated mice exhibit increased ear swelling that is not as severe as in mice with wild-type Matl1
|
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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• in tamoxifen-treated that is not as severe as in mice with wild-type Matl1
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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• in tamoxifen-treated mice that is not as severe as in mice with wild-type Matl1
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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