All Phenotypes Vps4b<tm1Thkn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vps4b^tm1Thkn
targeted mutation 1, Thomas Klein
MGI:6459255

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Vps4a^tm1.2Thkn/Vps4a⁺ Vps4b^tm1Thkn/Vps4b⁺	B6.129S2(Cg)-Vps4b^tm1Thkn Vps4a^tm1.2Thkn	MGI:6459272

Allelic Composition	Vps4a^tm1.2Thkn/Vps4a⁺ Vps4b^tm1Thkn/Vps4b⁺
Genetic Background	B6.129S2(Cg)-Vps4b^tm1Thkn Vps4a^tm1.2Thkn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vps4a^tm1.2Thkn mutation (0 available); any Vps4a mutation (15 available)
Vps4b^tm1Thkn mutation (0 available); any Vps4b mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell morphology ( J:236761 )

• mouse embryonic fibroblasts exhibit increased endo/lysosomal organelles with large multi-membrane structures compared with control cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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