Phenotypes associated with this allele

• Allele Symbol: Cc2d1a^tm1.2Thkn
• Allele Name: targeted mutation 1.1, Thomas Klein
• Allele ID: MGI:6458917
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cc2d1a^tm1.2Thkn/Cc2d1a^tm1.2Thkn	involves: 129S4/SvJae * BALB/cJ * C57BL/6 * SJL	MGI:6459276

Genotype
MGI:6459276

hm1

• Allelic Composition: Cc2d1a^tm1.2Thkn/Cc2d1a^tm1.2Thkn
• Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:236761 )

• mice die after birth

respiratory system

respiratory distress ( J:236761 )

• severe at birth

homeostasis/metabolism

cyanosis ( J:236761 )

• at birth

cellular

abnormal cell morphology ( J:236761 )

• mouse embryonic fibroblasts exhibit increased endo/lysosomal organelles compared with control cells

• however, large multi-membrane structures are not observed