Phenotypes associated with this allele

• Allele Symbol: Prdx1^tm1Yu
• Allele Name: targeted mutation 1, Dae-Yeul Yu
• Allele ID: MGI:6458773
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdx1^tm1Yu/Prdx1^tm1Yu	Not Specified	MGI:6716352

Genotype
MGI:6716352

hm1

• Allelic Composition: Prdx1^tm1Yu/Prdx1^tm1Yu
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased keratinocyte apoptosis ( J:306075 )

• after dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) treatment

homeostasis/metabolism

decreased incidence of tumors by chemical induction ( J:306075 )

• fewer skin tumors smaller than 4 mm after induction of squamous cell carcinoma (SCC) by dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA)

• normal number of skin tumors larger than 4 mm after induction of SCC by DMBA and TPA

integument

increased keratinocyte apoptosis ( J:306075 )

• after dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) treatment

thin skin ( J:306075 )

• after dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) treatment

neoplasm

decreased incidence of tumors by chemical induction ( J:306075 )

• fewer skin tumors smaller than 4 mm after induction of squamous cell carcinoma (SCC) by dimethylbenz[a]anthracene (DMBA) and 12-O-tetradecanoyl-phorbol-13-acetate (TPA)

• normal number of skin tumors larger than 4 mm after induction of SCC by DMBA and TPA