All Phenotypes Garem2<tm1.2Hkon> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Garem2^tm1.2Hkon
targeted mutation 1.2, Hiroaki Konishi
MGI:6456657

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Garem2^tm1.2Hkon/Garem2^tm1.2Hkon	involves: C57BL * C57BL/6JJcl * DBA	MGI:6456659

Allelic Composition	Garem2^tm1.2Hkon/Garem2^tm1.2Hkon
Genetic Background	involves: C57BL * C57BL/6JJcl * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Garem2^tm1.2Hkon mutation (0 available); any Garem2 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased exploration in new environment ( J:287781 )

increased coping response ( J:287781 )

• in a tail suspension test, mice exhibit longer latency to immobile behavior compared with wild-type mice

decreased anxiety-related response ( J:287781 )

• in an elevated plus maze and an open field

• however, anxiety response in a light/dark transition test is normal

increased vertical activity ( J:287781 )

• in an open field

abnormal social/conspecific interaction behavior ( J:287781 )

• mildly high social approaching behavior

nervous system

abnormal neurite morphology ( J:287781 )

• shorter neurite lengths in primary cultures

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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