Phenotypes associated with this allele

• Allele Symbol: Mir29a^em1Smoc
• Allele Name: endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• Allele ID: MGI:6455505
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mir29a^em1Smoc/Mir29a^em1Smoc	involves: C57BL/6J	MGI:6455506

Genotype
MGI:6455506

hm1

• Allelic Composition: Mir29a^em1Smoc/Mir29a^em1Smoc
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal digestive system physiology ( J:291233 )

• mice exposed to water avoidance stress to establish an irritable bowel syndrome (IBS) model exhibit decreased water content of feces and feces weight compared to controls and reduced intestinal hypersensitivity to colorectal distension pressures

behavior/neurological

hypoalgesia ( J:291233 )

• mice with water avoidance stress-induced IBS show decreased abdominal withdrawal reflex scores at all colorectal distension pressures except 15 mmHg indicating attenuated visceral hyperalgesia (ie, reduced intestinal hypersensitivity)