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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ctrlem1Toth
endonuclease-mediated mutation 1, Miklos Toth
MGI:6454999
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ctrlem1Toth/Ctrlem1Toth C57BL/6N-Ctrlem1Toth MGI:6455009


Genotype
MGI:6455009
hm1
Allelic
Composition		 Ctrlem1Toth/Ctrlem1Toth
Genetic
Background		 C57BL/6N-Ctrlem1Toth
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctrlem1Toth mutation (0 available); any Ctrl mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:294035 )
N
• mice exhibit normal response to induced pancreatitis
abnormal pancreas physiology ( J:294035 )
• cerulein-treated mice exhibit reduced intrapancreatic chymotrypsin activation compared with control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory