Phenotypes associated with this allele

• Allele Symbol: Endov^tm1Ial
• Allele Name: targeted mutation 1, Ingrun Alseth
• Allele ID: MGI:6452240
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Endov^tm1Ial/Endov^tm1Ial	involves: C57BL/6J * C57BL/6N	MGI:6452241

Genotype
MGI:6452241

hm1

• Allelic Composition: Endov^tm1Ial/Endov^tm1Ial
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

decreased incidence of tumors by chemical induction ( J:293118 )

• diethylnitrosamine (DEN)-treated mice show fewer and smaller tumors in the liver compared to wild-type mice

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:293118 )

N • mice exhibit normal metabolic parameters, including body weight, liver and plasma triglyceride levels, plasma nonesterified fatty acids, glucose levels, and C-peptide levels

decreased incidence of tumors by chemical induction ( J:293118 )

• diethylnitrosamine (DEN)-treated mice show fewer and smaller tumors in the liver compared to wild-type mice

behavior/neurological

behavior/neurological phenotype ( J:293118 )

N • mice exhibit normal behavior on the rotarod, treadmill acute exhaustion test, open field, and elevated zero maze, and normal grip strength