Analysis Tools
mortality/aging
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• fewer than expected mice are present at E16.5
• Background Sensitivity: mice on a mixed background exhibit improved survival compared to mice with increased backcrossing to C57BL/6
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craniofacial
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• in some of non-necrotic mice at E16.5
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• in some mice at E9.5
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• in all mice at E10.5 and some mice at E11.5
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• in most mice at E10.5 and all mice at E11.5
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• in some mice at E10.5 and in half of mice at E11.5
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• in some mice at E10.5
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• in all mice at E10.5 and some mice at E11.5
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• in most mice at E9.5
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• midface cleft at E16.5
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• in half of non-necrotic mice at E16.5
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absent snout
(
J:284772
)
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• in some of non-necrotic mice at E16.5
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• in most non-necrotic mice at E16.5
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growth/size/body
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• in some of non-necrotic mice at E16.5
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• midface cleft at E16.5
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• in half of non-necrotic mice at E16.5
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absent snout
(
J:284772
)
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• in some of non-necrotic mice at E16.5
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• in most non-necrotic mice at E16.5
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• in one mouse at E9.5 and in most mice at E10.5
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• growth arrest in one non-necrotic mouse at E16.5
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limbs/digits/tail
oligodactyly
(
J:284772
)
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• in all non-necrotic mice at E16.5
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• in all non-necrotic mice at E16.5
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micromelia
(
J:284772
)
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• in all non-necrotic mice at E16.5
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vision/eye
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• in most mice at E11.5
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nervous system
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• brain is shifted rostrally
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• in one non-necrotic mouse at E16.5
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cardiovascular system
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• in most mice at E9.5
• in some mice at E10.5 and E11.5
• in half of mice at E16.5
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embryo
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• in most mice at E9.5
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• in one mouse at E9.5 and in most mice at E10.5
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digestive/alimentary system
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• in half of non-necrotic mice at E16.5
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skeleton
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• in some of non-necrotic mice at E16.5
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