Analysis Tools
adipose tissue
| N |
• mice exhibit normal adaptive thermogenesis under any lighting condition
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Allele Symbol Allele Name Allele ID |
Opn3tm2c(EUCOMM)Wtsi targeted mutation 2c, Wellcome Trust Sanger Institute MGI:6449231 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal adaptive thermogenesis under any lighting condition
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal adaptive thermogenesis under any lighting condition
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• low beige content in inguinal white adipose tissue
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• larger size distribution
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• fed and fasted, cold-exposed mice impaired fat mobilization compared with control mice
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• reduced core body temperature following cold-exposure under full spectrum lighting
• however, mice raised without 480 nm light exhibit normal cold exposure response and tail temperatures are normal
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• unlike wild-type mice, fasted mice exhibit reduced elevation of serum glycerol compared with fed mice
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• following cold-exposure
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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