Phenotypes associated with this allele

• Allele Symbol: Dut^em1Bgv
• Allele Name: endonuclease-mediated mutation 1, Beata G Vertessy
• Allele ID: MGI:6443640
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dut^em1Bgv/Dut^em1Bgv	involves: FVB/N	MGI:6443641

Genotype
MGI:6443641

hm1

• Allelic Composition: Dut^em1Bgv/Dut^em1Bgv
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:290004 )

• embryos are only observed at early pre-implantation stages, with live embryos seen at E3.5 but not E8.5; embryos reach the blastocyst stage but die shortly after implantation

embryo

abnormal inner cell mass morphology ( J:290004 )

• 3.5 dpc blastocysts cultured in vitro show a smaller inner cell mass (ICM) and after 4 days in culture, ICM clump size is smaller

abnormal trophectoderm morphology ( J:290004 )

• 3.5 dpc blastocysts cultured in vitro for 4 days show a reduced size of the trophectoderm