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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cops8em1(IMPC)Ccpcz
endonuclease-mediated mutation 1, Institute of Molecular Genetics
MGI:6442547
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cops8em1(IMPC)Ccpcz/Cops8em1(IMPC)Ccpcz C57BL/6NCrl-Cops8em1(IMPC)Ccpcz/Ph MGI:7628951
ht2
 		Cops8em1(IMPC)Ccpcz/Cops8+ C57BL/6NCrl-Cops8em1(IMPC)Ccpcz/Ph MGI:7628950


Genotype
MGI:7628951
hm1
Allelic
Composition		 Cops8em1(IMPC)Ccpcz/Cops8em1(IMPC)Ccpcz
Genetic
Background		 C57BL/6NCrl-Cops8em1(IMPC)Ccpcz/Ph
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cops8em1(IMPC)Ccpcz mutation (1 available); any Cops8 mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:7628950
ht2
Allelic
Composition		 Cops8em1(IMPC)Ccpcz/Cops8+
Genetic
Background		 C57BL/6NCrl-Cops8em1(IMPC)Ccpcz/Ph
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cops8em1(IMPC)Ccpcz mutation (1 available); any Cops8 mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged heart ( J:211773 )
IMPC - CCP-IMG

endocrine/exocrine glands
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

growth/size/body
enlarged heart ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory