Phenotypes associated with this allele

• Allele Symbol: Flt3^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6442533
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Flt3^em1(IMPC)Ccpcz/Flt3^em1(IMPC)Ccpcz	C57BL/6NCrl-Flt3^em1(IMPC)Ccpcz/Ph	MGI:7414898

Genotype
MGI:7414898

hm1

• Allelic Composition: Flt3^{em1(IMPC)Ccpcz}/Flt3^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Flt3^{em1(IMPC)Ccpcz}/Ph

Data Sources

IMPC Data for Flt3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

decreased lean body mass ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

decreased NK cell number ( J:211773 )

IMPC - CCP-IMG

decreased effector memory T-helper cell number ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

immune system

decreased NK cell number ( J:211773 )

IMPC - CCP-IMG

decreased effector memory T-helper cell number ( J:211773 )

♀

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

IMPC - CCP-IMG

limbs/digits/tail

abnormal digit morphology ( J:211773 )

IMPC - CCP-IMG

muscle

abnormal skeletal muscle morphology ( J:211773 )

♀

IMPC - CCP-IMG

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - CCP-IMG

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - CCP-IMG

hydrometra ( J:211773 )

♀

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - CCP-IMG