All Phenotypes Gphr<ex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gphr^ex
explorer
MGI:6441474

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gphr^ex/Gphr^ex	C57BL/6J-Gphr^ex	MGI:6441546

Allelic Composition	Gphr^ex/Gphr^ex
Genetic Background	C57BL/6J-Gphr^ex

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gphr^ex mutation (0 available); any Gphr mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal T cell morphology ( J:287198 )

• increased CD44 expression in CD3+, CD4+, and CD8+ T cells

abnormal T cell number ( J:287198 )

• reduced CD3+, CD4+, and CD8+ T cell frequencies

immune system

abnormal T cell morphology ( J:287198 )

• increased CD44 expression in CD3+, CD4+, and CD8+ T cells

abnormal T cell number ( J:287198 )

• reduced CD3+, CD4+, and CD8+ T cell frequencies

growth/size/body

decreased birth body size ( J:287198 )

• 40% smaller than WT littermates

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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