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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpr89ex
explorer
MGI:6441474
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gpr89ex/Gpr89ex C57BL/6J-Gpr89ex MGI:6441546


Genotype
MGI:6441546
hm1
Allelic
Composition		 Gpr89ex/Gpr89ex
Genetic
Background		 C57BL/6J-Gpr89ex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr89ex mutation (0 available); any Gpr89 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell morphology ( J:287198 )
• increased CD44 expression in CD3+, CD4+, and CD8+ T cells
abnormal T cell number ( J:287198 )
• reduced CD3+, CD4+, and CD8+ T cell frequencies

immune system
abnormal T cell morphology ( J:287198 )
• increased CD44 expression in CD3+, CD4+, and CD8+ T cells
abnormal T cell number ( J:287198 )
• reduced CD3+, CD4+, and CD8+ T cell frequencies

growth/size/body
decreased birth body size ( J:287198 )
• 40% smaller than WT littermates




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory