Phenotypes associated with this allele
Allelic
Composition |
Card14em3Tshu/Card14+
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Genetic
Background |
involves: C57BL/6 |
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Card14em3Tshu mutation
(0 available);
any
Card14 mutation
(38 available)
|
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integument
|
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• redness and swelling of ears up to approximately 12 weeks of age
|
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• epidermal thickening in the tails at 18 and 36 days of age
|
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• mice develop a weak psoriasis-like phenotype
|
immune system
|
|
• redness and swelling of ears up to approximately 12 weeks of age
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Card14em3Tshu mutation
(0 available);
any
Card14 mutation
(38 available)
Il17atm1Cdon mutation
(0 available);
any
Il17a mutation
(22 available)
|
|
|
immune system
|
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• the increase in ear thickness indicative of skin inflammation that is seen in heterozygous Card14em3Tshu mice is partially reduced
|
Analysis Tools