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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc38a1tm1.1Ttaka
targeted mutation 1.1, Takeshi Takarada
MGI:6441049
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Slc38a1tm1.1Ttaka/Slc38a1tm1.1Ttaka
Tsc1tm1Djk/Tsc1+
Tg(Syn1-cre)671Jxm/0 		involves: 129S4/SvJae * C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj MGI:6441084
cn2
 		Slc38a1tm1.1Ttaka/Slc38a1tm1.1Ttaka
Tg(Syn1-cre)671Jxm/0 		involves: C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj MGI:6441082


Genotype
MGI:6441084
cn1
Allelic
Composition		 Slc38a1tm1.1Ttaka/Slc38a1tm1.1Ttaka
Tsc1tm1Djk/Tsc1+
Tg(Syn1-cre)671Jxm/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc38a1tm1.1Ttaka mutation (0 available); any Slc38a1 mutation (32 available)
Tg(Syn1-cre)671Jxm mutation (1 available)
Tsc1tm1Djk mutation (2 available); any Tsc1 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:288818 )
N
• normal susceptibility to ischemic brain injury after applying middle cerebral artery occlusion (MCAO)




Genotype
MGI:6441082
cn2
Allelic
Composition		 Slc38a1tm1.1Ttaka/Slc38a1tm1.1Ttaka
Tg(Syn1-cre)671Jxm/0
Genetic
Background		 involves: C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc38a1tm1.1Ttaka mutation (0 available); any Slc38a1 mutation (32 available)
Tg(Syn1-cre)671Jxm mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased susceptibility to ischemic brain injury ( J:288818 )
• after applying middle cerebral artery occlusion (MCAO)
decreased cerebral infarct size ( J:288818 )
• as judged from smaller NeuN- or MAP2-negative area after applying middle cerebral artery occlusion (MCAO)

nervous system
decreased susceptibility to ischemic brain injury ( J:288818 )
• after applying middle cerebral artery occlusion (MCAO)
decreased cerebral infarct size ( J:288818 )
• as judged from smaller NeuN- or MAP2-negative area after applying middle cerebral artery occlusion (MCAO)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory