Phenotypes associated with this allele

• Allele Symbol: Fah^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6423839
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fah^em1(IMPC)Mbp/Fah^em1(IMPC)Mbp	C57BL/6N-Fah^em1(IMPC)Mbp/MbpMmucd	MGI:6492836
ht2	Fah^em1(IMPC)Mbp/Fah^+	C57BL/6N-Fah^em1(IMPC)Mbp/MbpMmucd	MGI:6731314

Genotype
MGI:6492836

hm1

• Allelic Composition: Fah^em1(IMPC)Mbp/Fah^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Fah^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Fah

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6731314

ht2

• Allelic Composition: Fah^em1(IMPC)Mbp/Fah⁺
• Genetic Background: C57BL/6N-Fah^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Fah

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - UCD

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

enlarged testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

small liver ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

enlarged testis ( J:211773 )

♂

IMPC - UCD

vision/eye

abnormal retina vasculature morphology ( J:211773 )

IMPC - UCD

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

IMPC - UCD