Phenotypes associated with this allele

• Allele Symbol: Tmcc2^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6423822
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmcc2^em1(IMPC)Mbp/Tmcc2^em1(IMPC)Mbp	C57BL/6N-Tmcc2^em1(IMPC)Mbp/MbpMmucd	MGI:6696943
ht2	Tmcc2^em1(IMPC)Mbp/Tmcc2^+	C57BL/6N-Tmcc2^em1(IMPC)Mbp/MbpMmucd	MGI:7317082

Genotype
MGI:6696943

hm1

• Allelic Composition: Tmcc2^em1(IMPC)Mbp/Tmcc2^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Tmcc2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tmcc2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

integument

abnormal skin appearance ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:7317082

ht2

• Allelic Composition: Tmcc2^em1(IMPC)Mbp/Tmcc2⁺
• Genetic Background: C57BL/6N-Tmcc2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tmcc2

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

IMPC - UCD

digestive/alimentary system

abnormal cecum morphology ( J:211773 )

IMPC - UCD

enlarged cecum ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal gallbladder morphology ( J:211773 )

♀

IMPC - UCD

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

♂

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

liver/biliary system

abnormal gallbladder morphology ( J:211773 )

♀

IMPC - UCD

enlarged gallbladder ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

♀

IMPC - UCD