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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		nob10
no b wave 10
MGI:6423083
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		nob10/nob10 B6.Cg-nob10/Boc MGI:6423094


Genotype
MGI:6423094
hm1
Allelic
Composition		 nob10/nob10
Genetic
Background		 B6.Cg-nob10/Boc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
nob10 mutation (1 available); any nob10 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
retina photoreceptor degeneration ( J:287579 )
• histology and OCT show a thin retina with 20-30% photoreceptor loss, slow progressive loss after that

vision/eye
retina photoreceptor degeneration ( J:287579 )
• histology and OCT show a thin retina with 20-30% photoreceptor loss, slow progressive loss after that
retina spots ( J:287579 )
• evident by 6 months of age
abnormal electroretinogram waveform feature ( J:287579 )
• ERG at 3 weeks of age shows no b wave rod-mediated photoresponse and abnormal cone-mediated response




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory