All Phenotypes Rnf43<em1Mage> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rnf43^em1Mage
endonuclease-mediated mutation 1, Markus Gerhard
MGI:6403353

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf43^em1Mage/Rnf43^em1Mage	Not Specified	MGI:6403437

Allelic Composition	Rnf43^em1Mage/Rnf43^em1Mage
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf43^em1Mage mutation (0 available); any Rnf43 mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

digestive/alimentary phenotype ( J:276360 )

N	• normal intestinal and colon epithelium morphology and cell proliferation at age 12, 24 and 40 weeks

• proliferation into lumen and thicker mucosa at age 24 and 40 weeks

• multifocal hyperplasia at age 16 weeks

abnormal stomach wall morphology ( J:276360 )

• proliferation into lumen and thicker mucosa at age 24 and 40 weeks

• multifocal hyperplasia at age 16 weeks

• thicker mucosa at age 24 and 40 weeks

immune system

immune system phenotype ( J:276360 )

N	• no inflammation of stomach

mortality/aging

mortality/aging ( J:276360 )

N	• viable and born at expected Mendelian ratio

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