About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfatem1(IMPC)Ccpcz
endonuclease-mediated mutation 1, Institute of Molecular Genetics
MGI:6399888
Summary 2 genotypes


Genotype
MGI:7415175
hm1
Allelic
Composition		 Zfatem1(IMPC)Ccpcz/Zfatem1(IMPC)Ccpcz
Genetic
Background		 C57BL/6NCrl-Zfatem1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfatem1(IMPC)Ccpcz mutation (1 available); any Zfat mutation (74 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryo size ( J:211773 )
IMPC - CCP-IMG

growth/size/body
embryonic growth retardation ( J:211773 )
IMPC - CCP-IMG
abnormal embryo size ( J:211773 )
IMPC - CCP-IMG

mortality/aging




Genotype
MGI:7415174
ht2
Allelic
Composition		 Zfatem1(IMPC)Ccpcz/Zfat+
Genetic
Background		 C57BL/6NCrl-Zfatem1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfatem1(IMPC)Ccpcz mutation (1 available); any Zfat mutation (74 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged heart ( J:211773 )
IMPC - CCP-IMG

craniofacial

endocrine/exocrine glands
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

growth/size/body
enlarged heart ( J:211773 )
IMPC - CCP-IMG
abnormal tooth morphology ( J:211773 )
IMPC - CCP-IMG
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

skeleton




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory