About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hmbstm2.1Rjde
targeted mutation 2.1, Robert J Desnick
MGI:6393999
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hmbstm2.1Rjde/Hmbstm2.1Rjde involves: 129/Sv * C57BL/6 MGI:6394001
ht2
 		Hmbstm1.1Rjde/Hmbstm2.1Rjde involves: 129/Sv * C57BL/6 MGI:6394010


Genotype
MGI:6394001
hm1
Allelic
Composition		 Hmbstm2.1Rjde/Hmbstm2.1Rjde
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmbstm2.1Rjde mutation (0 available); any Hmbs mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:275245 )
• embryonic lethal, however time of lethality is not specified




Genotype
MGI:6394010
ht2
Allelic
Composition		 Hmbstm1.1Rjde/Hmbstm2.1Rjde
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmbstm1.1Rjde mutation (0 available); any Hmbs mutation (24 available)
Hmbstm2.1Rjde mutation (0 available); any Hmbs mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:275245 )
• all die by P30

growth/size/body
decreased body size ( J:275245 )
• mice are severely runted
cachexia ( J:275245 )




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory