Phenotypes associated with this allele

• Allele Symbol: Hspb8^tm1.1Vti
• Allele Name: targeted mutation 1.1, Vincent Timmerman
• Allele ID: MGI:6392625
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hspb8^tm1.1Vti/Hspb8^tm1.1Vti	involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl	MGI:6392830

Genotype
MGI:6392830

hm1

• Allelic Composition: Hspb8^tm1.1Vti/Hspb8^tm1.1Vti
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal skeletal muscle morphology ( J:284796 )

• gastrocnemius muscle shows accumulation of pathologic mitochondria, many showing degenerating cristae and abnormal matrix

• however, Z-disc structure is preserved and atrophic or necrotic fibers are not seen

behavior/neurological

behavior/neurological phenotype ( J:284796 )

N • mice do not develop motor or sensory deficits, compound motor action potential abnormalities

nervous system

nervous system phenotype ( J:284796 )

N • mice do not show compound motor action potential abnormalities or axon loss