About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mxra8em2Diam
endonuclease-mediated mutation 2, Michael S Diamond
MGI:6378754
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mxra8em2Diam/Mxra8em2Diam C57BL/6J-Mxra8em2Diam MGI:6378763


Genotype
MGI:6378763
hm1
Allelic
Composition
Mxra8em2Diam/Mxra8em2Diam
Genetic
Background
C57BL/6J-Mxra8em2Diam
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mxra8em2Diam mutation (0 available); any Mxra8 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice inoculated with Chikungunya virus (CHIKV, Asian strain AF15561 or East/Central/South African strain LR 2006) subcutaneously in the feet show reduced levels of CHIKV infection compared to wild-type mice, with decreased viral titers and foot swelling
• MEFs show reduced CHIKV infection





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory