About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(CAG-PTPN1,-EGFP)Mtr
targeted mutation 1, Michel L Tremblay
MGI:6378624
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(CAG-PTPN1,-EGFP)Mtr/Gt(ROSA)26Sor+
Tg(Pbsn-cre)4Prb/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 MGI:6378625


Genotype
MGI:6378625
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(CAG-PTPN1,-EGFP)Mtr/Gt(ROSA)26Sor+
Tg(Pbsn-cre)4Prb/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(CAG-PTPN1,-EGFP)Mtr mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Pbsn-cre)4Prb mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
prostate gland anterior lobe hyperplasia ( J:231906 )
• mice show a moderate incidence of epithelial hyperplasia in the anterior prostate
increased prostate intraepithelial neoplasia incidence ( J:231906 )
• one mouse shows a prostatic intraepithelial neoplasia (mPIN) in the dorsolateral prostate

neoplasm
increased prostate intraepithelial neoplasia incidence ( J:231906 )
• one mouse shows a prostatic intraepithelial neoplasia (mPIN) in the dorsolateral prostate

reproductive system
prostate gland anterior lobe hyperplasia ( J:231906 )
• mice show a moderate incidence of epithelial hyperplasia in the anterior prostate
increased prostate intraepithelial neoplasia incidence ( J:231906 )
• one mouse shows a prostatic intraepithelial neoplasia (mPIN) in the dorsolateral prostate




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory