All Phenotypes Slc12a8<em1Imai> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc12a8^em1Imai
endonuclease-mediated mutation 1, Shin-ichiro Imai
MGI:6370147

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc12a8^em1Imai/Slc12a8^em1Imai	B6.Cg-Slc12a8^em1Imai	MGI:6370154

Allelic Composition	Slc12a8^em1Imai/Slc12a8^em1Imai
Genetic Background	B6.Cg-Slc12a8^em1Imai

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc12a8^em1Imai mutation (0 available); any Slc12a8 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:280135 )

• fewer than expected mice were born

homeostasis/metabolism

abnormal nucleotide metabolism ( J:280135 )

• decreased NAD+ levels in the jejunum and ileum associated with nicotinamide mononucleotide transport

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24