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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ct55em1Xdzg
endonuclease-mediated mutation 1, Xiao-Dong Zhang
MGI:6370008
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ct55em1Xdzg/Ct55em1Xdzg involves: C57BL/6 MGI:6370019


Genotype
MGI:6370019
hm1
Allelic
Composition		 Ct55em1Xdzg/Ct55em1Xdzg
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ct55em1Xdzg mutation (0 available); any Ct55 mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
decreased susceptibility to induced colitis ( J:280149 )
• AOM/DSS-treated mice exhibit reduced susceptibility to weight loss, rectal prolapse and visible tumors compared with wild-type mice

growth/size/body
decreased susceptibility to weight loss ( J:280149 )
• in AOM/DSS-treated mice

neoplasm
decreased incidence of induced tumors ( J:280149 )
• fewer and smaller sized tumors in AOM/DSS-treated mice

immune system
decreased susceptibility to induced colitis ( J:280149 )
• AOM/DSS-treated mice exhibit reduced susceptibility to weight loss, rectal prolapse and visible tumors compared with wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory