Phenotypes associated with this allele

• Allele Symbol: Tm9sf2^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:6369354
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tm9sf2^em1(IMPC)Tcp/Tm9sf2^em1(IMPC)Tcp	C57BL/6N-Tm9sf2^em1(IMPC)Tcp/Tcp	MGI:6493150
ht2	Tm9sf2^em1(IMPC)Tcp/Tm9sf2^+	C57BL/6NCrl-Tm9sf2^em1(IMPC)Tcp/TcpMmucd	MGI:8264612
ht3	Tm9sf2^em1(IMPC)Tcp/Tm9sf2^+	C57BL/6N-Tm9sf2^em1(IMPC)Tcp/Tcp	MGI:6696942

Genotype
MGI:6493150

hm1

• Allelic Composition: Tm9sf2^em1(IMPC)Tcp/Tm9sf2^em1(IMPC)Tcp
• Genetic Background: C57BL/6N-Tm9sf2^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Tm9sf2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:8264612

ht2

• Allelic Composition: Tm9sf2^em1(IMPC)Tcp/Tm9sf2⁺
• Genetic Background: C57BL/6NCrl-Tm9sf2^em1(IMPC)Tcp/TcpMmucd

reproductive system

abnormal fertility/fecundity ( J:374598 )

• mice did not breed successfully

Genotype
MGI:6696942

ht3

• Allelic Composition: Tm9sf2^em1(IMPC)Tcp/Tm9sf2⁺
• Genetic Background: C57BL/6N-Tm9sf2^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Tm9sf2

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:211773 )

♂

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP