Phenotypes associated with this allele

• Allele Symbol: Zfp418^em#Juli
• Allele Name: endonuclease-mediated mutation, Junming Li
• Allele ID: MGI:6369036
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp418^em#Juli/Zfp418^em#Juli	Not Specified	MGI:6369042

Genotype
MGI:6369042

hm1

• Allelic Composition: Zfp418^em#Juli/Zfp418^em#Juli
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiac hypertrophy ( J:251673 )

• under aortic banding induced cardiac hypertrophy model, myocytes size and fibrosis were exacerbated compared to the controls

heart left ventricle hypertrophy ( J:251673 )

• significantly increased left ventricular cross-sectional area and a more significant fibrosis in the myocardium of aortic banding treated mice compared to the controls

muscle

heart left ventricle hypertrophy ( J:251673 )

• significantly increased left ventricular cross-sectional area and a more significant fibrosis in the myocardium of aortic banding treated mice compared to the controls

growth/size/body

cardiac hypertrophy ( J:251673 )

• under aortic banding induced cardiac hypertrophy model, myocytes size and fibrosis were exacerbated compared to the controls

heart left ventricle hypertrophy ( J:251673 )

• significantly increased left ventricular cross-sectional area and a more significant fibrosis in the myocardium of aortic banding treated mice compared to the controls