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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mirc29tm1.1Wtsi
targeted mutation 1.1, Wellcome Trust Sanger Institute
MGI:6367595
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mirc29tm1.1Wtsi/Mirc29tm1.1Wtsi C57BL/6N-Mirc29tm1.1Wtsi MGI:6367620
cx2
 		Mirc29tm1.1Wtsi/Mirc29tm1.1Wtsi
Mirc33tm1.1Wtsi/Mirc33tm1.1Wtsi 		C57BL/6N-Mirc29tm1.1Wtsi Mirc33tm1.1Wtsi MGI:6367622


Genotype
MGI:6367620
hm1
Allelic
Composition		 Mirc29tm1.1Wtsi/Mirc29tm1.1Wtsi
Genetic
Background		 C57BL/6N-Mirc29tm1.1Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc29tm1.1Wtsi mutation (0 available); any Mirc29 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:267719 )
• slight decrease in body weight
• however, mice develop normally without any obvious alterations

renal/urinary system
ischuria ( J:267719 )
• old mice develop urinary retention with incomplete penetrance

cardiovascular system
cardiovascular system phenotype ( J:267719 )
N
• no fibrotic accumulation in the coronary arteries is seen




Genotype
MGI:6367622
cx2
Allelic
Composition		 Mirc29tm1.1Wtsi/Mirc29tm1.1Wtsi
Mirc33tm1.1Wtsi/Mirc33tm1.1Wtsi
Genetic
Background		 C57BL/6N-Mirc29tm1.1Wtsi Mirc33tm1.1Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc29tm1.1Wtsi mutation (0 available); any Mirc29 mutation (1 available)
Mirc33tm1.1Wtsi mutation (0 available); any Mirc33 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:267719 )
• life span is reduced to a median of 23 days

growth/size/body
decreased body weight ( J:267719 )
• mice show reduced body weight few days after birth
postnatal growth retardation ( J:267719 )
• striking growth retardation

cardiovascular system
abnormal heart morphology ( J:267719 )
• necrotic areas with collagen accumulation are seen in hearts

homeostasis/metabolism
increased fasting circulating glucose level ( J:267719 )
• fasted mice exhibit hyperglycemia
decreased circulating glucose level ( J:267719 )
• reduction in serum glucose concentration in nonfasted mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory